Science

REVOLUTIONIZING HEALTHCARE WITH
PEPTIDE-BASED THERAPIES

P140

Autoimmunity

Clinic

CDx

Autoimmunity

Clinic

Kapiglucagon

Type 1 Diabetes

Preclinic

BioAMB

Antifungal

Preclinic

BioCIN

Antibiotic

Preclinic

Rethinking Therapeutic Frontiers

ImmuPharma is pioneering a new generation of precision therapies to address major global health challenges, including autoimmune diseases, infectious diseases, and metabolic disorders such as type 1 diabetes.

Our approach goes beyond symptom management — we aim to target the underlying mechanisms of disease and unlock transformative therapeutic solutions. Leveraging deep expertise in peptide science, we develop first-in-class therapeutics and enabling technologies designed to reshape treatment paradigms.

In parallel with our work in immunology and infectious diseases, ImmuPharma is advancing Kapiglucagon, a proprietary glucagon prodrug technology designed to enable next-generation artificial pancreas systems for type 1 diabetes. By overcoming the long-standing formulation limitations of native glucagon, Kapiglucagon has the potential to support the development of dual-hormone automated insulin delivery systems, bringing diabetes management closer to fully autonomous glucose control.

Through internally driven innovation and strategic partnerships, ImmuPharma aims to deliver high-impact therapeutic assets capable of transforming patient care while creating sustainable long-term value.

Autoimmunity: Restoring Immune Homeostasis

Current treatments in autoimmunity rely on suppressing or modulating the immune system, often with limited efficacy and safety issues.

P140 (Lupuzor™, forigerimod) represents a breakthrough: a first-in-class immunormalizer designed to selectively normalize abnormal immune pathways while preserving healthy immunity.

This unique mechanism aims to achieve durable remission rather than temporary control.

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Precision Through Companion Diagnostics

To maximize therapeutic impact, Immuharma has developed a next-generation companion diagnostic integrating multi-layered diagnostic logic to guide both patient selection and treatment adaptation.

At the heart of this platform is the discovery of Type M, a newly defined immune endotype present in up to 80% of patients across major autoimmune diseases.

Rapid and simple testing
High diagnostic performance
Identification of “super-responders” to P140

This integrated strategy enables patient stratification and real-time response monitoring, paving the way for personalized and potentially curative treatment.

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Type 1 Diabetes – Enabling Dual-Hormone Artificial Pancreas Systems

ImmuPharma is developing Kapiglucagon, a proprietary glucagon prodrug designed to overcome the long-standing stability limitations of native glucagon in aqueous formulations. While advances in insulin pumps and continuous glucose monitoring have significantly improved diabetes management, the development of fully automated dual-hormone artificial pancreas systems remains constrained by the lack of a stable glucagon suitable for continuous pump delivery. Kapiglucagon is designed to provide a highly soluble, stable glucagon source compatible with pump reservoirs, regenerating native glucagon following subcutaneous administration. This technology has the potential to enable the next generation of automated insulin-glucagon delivery systems, bringing diabetes management closer to truly physiological and autonomous glucose control.

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Anti-Infectives: Combating Resistance

ImmuPharma is also addressing the growing global threat of antimicrobial resistance with novel anti-infective therapies:

BioAMB: A next-generation amphotericin-B therapy with improved safety, simple injection, and first-line potential in invasive fungal infections.
BioCIN: An innovative vancomycin-based therapy offering better tolerability, simplified administration, and stronger efficacy against MRSA and other Gram-positive infections.

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Our Vision

By leveraging innovative peptide science and targeted therapeutic strategies, ImmuPharma is building a pipeline designed to address major global health challenges, including autoimmune diseases, infectious diseases, and metabolic disorders such as type 1 diabetes.

Our ambition is to move beyond symptom management toward disease-modifying and technology-enabling solutions that target the underlying mechanisms of disease. Through a portfolio of first-in-class therapeutics and enabling technologies, we aim to reshape treatment paradigms across multiple therapeutic areas.

By combining internally driven innovation with strategic partnerships, ImmuPharma seeks to develop high-impact therapeutic assets capable of transforming patient care while creating sustainable long-term value.

By combining innovative therapies and precision diagnostics, ImmuPharma is building a pipeline designed to change disease trajectories.

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Prodrug

What is a Prodrug?

A prodrug is a pharmacologically inactive or much less active compound that is converted inside the body (usually by metabolic enzymes) into the active drug that actually produces the therapeutic effect.

Lisa Baderoon

Non-Executive Director and Head of Investor Relations

Lisa has spent over 25 years working within the City of London being involved with a diverse portfolio of clients from a variety of sectors but with a leaning towards emerging, high growth businesses advising both private and public companies on their financial and corporate strategies aligned to stakeholder and investor interests, as well as a strong acumen in media communication. During this time, she has been involved in a multitude of client transactions spanning private fund raisings, Initial Public Offerings (IPOs), secondary high profile capital raisings and mergers and acquisitions both in the UK and internationally.

Lisa had a successful career spanning 20 years as a Partner at Buchanan Communications, one of the leading City financial public relations agencies. As one of the youngest Board members, she was involved in the successful five-year earnout, as part of Buchanan being acquired by the FTSE 100 rated WPP Plc in 1997.

Lisa founded Just B Communications Ltd in 2012 with the key objective of working with a more select number of clients and providing a greater degree of bespoke advisory services thus becoming more integral to the day to day corporate and strategic development for these businesses. She has successfully advised a number of public and private companies, at Board level, on corporate strategy, stakeholder and investor communications, capital raisings, dual listings, licensing and M&A. Media profiling, where required, has also played an important role in advisory activities.

Lisa was appointed Head of Investor Relations at ImmuPharma in 2012 and most recently appointed as a Non-Executive Director in July 2021.

Ketan Patel

Independent Non-Executive Director

Ketan is an experienced investment professional who brings extensive expertise in financial markets, with a particular focus on the UK healthcare and life science sectors. He has been a long-term investor in UK markets, working as both an analyst and Fund Manager, managing institutional, retail, and charity mandates. Ketan began his career at JP Morgan before moving to Insight Investment, where he served as a global Pharmaceutical and Healthcare analyst. He then spent over 20 years at EdenTree Investment Management, where he was responsible for UK equity and global equity income strategies, consistently delivering upper-quartile performance.

Ketan combines rigorous fundamental analysis with risk-focused investment strategies. He is also a published thought leader on sustainability and investment themes. Ketan is a CFA Charterholder and holds an MSc in Economic History from the London School of Economics, an MSc in Geography from King’s College London, and a BA (Hons) in History and Geography from Queen Mary University, London.

Dr Laurence Reilly MD, LLM

Senior Independent Non-Executive Director

Dr Laurence Reilly has been appointed as Senior independent Non-Executive Director and Chair of the Audit Committee. Dr Reilly brings extensive experience in managing late-stage clinical programs through to approval, in addition to commercial and business development experience.

He is currently Vice President of Research & Investments, working with Royalty Pharma, a New York based life science investment company focussing on acquisition of biopharmaceutical royalties and funding of innovation across the biopharmaceutical industry.

Through his consulting practice (Acumen Life Science Investment Consulting) Dr Reilly has provided strategic consulting and due-diligence services to biotech companies, life science venture capital and private equity clients. He also served as Chief Medical Officer for Cellectar Biosciences, New Jersey, a late-stage oncology biotech company. Prior to founding his consulting practice, Dr Reilly served as Chief Scientific Officer and Vice President at Avillion, a drug development company focused on the co-development and financing of drug candidates, where he was responsible for clinical and strategic oversight of co-development programs and partnering with both large pharma and biotech, including Pfizer, Merck KGaA and AstraZeneca. Dr. Reilly previously served as a Clinician – Clinical Development & Medical Oversight at Pfizer and at Lundbeck as Medical & Scientific Advisor.

Dr Reilly earned his medical degree from the University of Liverpool Medical School, U.K., and practiced as Neurosurgery Resident at Queen Elizabeth University Hospital in Birmingham. Dr Reilly also holds a Masters Degree in Law from De Montfort University, U.K.

Dr Tim Franklin PhD, MBA

Chief Operating Officer

Tim has 38 years’ experience in the biopharmaceutical industry. He worked in clinical research, sales & marketing, and global strategic marketing for Warner Lambert, Wellcome and SmithKline Beecham. He later moved to the capital markets where he became a top-ranked pharmaceuticals analyst at Dresdner Kleinwort investment bank. He applied his experience to stock selection at hedge funds and advised several small biotechnology companies on corporate and commercial strategy and access to capital. He holds a BSc in Medicinal Chemistry and a PhD in Pharmacology from Loughborough University and an MBA from Warwick Business School.

Dr Laura Mauran-Ambrosino Ph.D.

Head of R&D

Born in Montpellier, France, Dr. Mauran-Ambrosino obtained her PhD in Chemistry from the Université de Bordeaux as a CIFRE fellow under the co-supervision of Dr. Goudreau. She then conducted postdoctoral research in cell biology at the Centre Hospitalier Universitaire (CHU) Pellegrin in Bordeaux.

In 2018, she joined Ureka, where she established both the Biology and Analytical Chemistry departments. In 2021, she became Chief Scientific Officer of Ureka Pharma. Since 2025, Dr. Mauran-Ambrosino has served as Head of R&D of the ImmuPharma Group.

Dr. Mauran-Ambrosino was a key contributor to the development of several programs, including BioAMB, BioCIN, the P140 companion diagnostic, and Kapiglucagon.

Ashley Clarke ACA

Chief Financial Officer & Company Secretary

Ashley brings over a decade of experience in the financial sector. She began her career at a Big Four accounting firm and later advanced her professional expertise by earning her ACA qualification with a respected local firm.

Her professional journey is rooted in auditing, where she developed expertise working with a diverse portfolio of audit and non-audit clients across various industries. Ashley’s experience spans from supporting SMEs to managing large international group consolidations, giving her a comprehensive understanding of financial management across different business scales.

Ashley has been closely involved with the company’s accounts for several years via outsourced accountants, providing her with deep familiarity with its operations. Now, as Group CFO and Company Secretary, she is poised to leverage her extensive knowledge to drive strategic financial growth and ensure robust fiscal management.

Dr Sébastien R. Goudreau Ph.D.

Chief Scientific Officer

Born in Sherbrooke, Québec, Canada, Dr. Sébastien Goudreau obtained his PhD in Chemistry from the Université de Montréal as an NSERC fellow before conducting postdoctoral research at ETH Zürich as an FRQNT fellow. He later returned to Canada, where he co-founded FindMolecule Inc. and worked in the pharmaceutical industry.

Dr. Goudreau joined ImmuPharma in 2014 as Research Director and established the Ureka research laboratories in Bordeaux. Following the merger of ELRO and Ureka in 2019, he became Chief Scientific Officer of Ureka Pharma. In 2021, he was appointed Chief Executive Officer of ImmuPharma Biotech, and since 2025 he has served as Chief Scientific Officer of the ImmuPharma Group.

Dr. Goudreau and his team are credited with the discovery and development of several innovative programs, including BioAMB, BioCIN, the P140 companion diagnostic, and Kapiglucagon.

Tim McCarthy FCCA, MBA

Chief Executive Officer

Tim has 40 years’ international senior level business experience in high growth biotech, healthcare and technology companies. He is also Chairman of Incanthera plc. Tim was formerly Chairman of 4basebio plc and CEO and CFO of a number of UK public listed and private companies including, Alizyme plc and Peptide Therapeutics Group plc, and has a core understanding of AIM and its regulatory processes. Co-founding a number of healthcare and biotechnology companies, he has helped raise substantial amounts of equity capital and also advised and worked at Board level for a diverse range of companies internationally, in areas such as business strategy, mergers & acquisitions, due diligence and licensing.

REVOLUTIONIZING HEALTHCARE WITHPEPTIDE-BASED THERAPIES

Rethinking Therapeutic Frontiers

Autoimmunity: Restoring Immune Homeostasis

Precision Through Companion Diagnostics

Type 1 Diabetes – Enabling Dual-Hormone Artificial Pancreas Systems

Anti-Infectives: Combating Resistance

Our Vision

REVOLUTIONIZING HEALTHCARE WITH
PEPTIDE-BASED THERAPIES